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[Epub ahead of print] PubMed PMID: 25389917
54 nM for the inhibition of survivin promoter activity
Formula: C32H46N4O6S
PNU-120596 augments the effects of donepezil on learning and memory in aged rodents and non-human primates
ABT-492 Size:2mg solid [Epub ahead of print] PubMedABT 492 is a non zwitterionic fluoroquinolone antibiotic under development for for the treatment of respiratory and skin infections. Delafloxacin demonstrates excellent antibacterial potency and exhibits a low probability for the selection of resistant mutants in MRSA. Although mutants can be selected at low frequencies in vitro from quinolone resistant isolates, delafloxacin MICs and MPCs remain low and a fitness cost can be observed. Consequently